Case Study A6 - Antibody Identification - Panel #3

Because HTLA antibodies were suspected, Panel #1 was repeated by papain-IAT and four ABO-compatible E-negative cord red cells were tested.

Cell Rh Rhesus Kell Duffy Kidd MNSs P Lewis Lu Results Cell
    C D E c e Cw K k Kpa Fya Fyb Jka Jkb M N S s P1 Lea Leb Lua ENZ
IAT*		  
1 rr 0 0 0 + + 0 0 + 0 + 0 + 0 0 + + + +S + 0 0 0 1
2 rr 0 0 0 + + 0 0 + 0 + 0 + 0 0 + + + +S + 0 0 0 2
3 rr 0 0 0 + + 0 0 + 0 + + 0 + 0 + + 0 + 0 + 0 0 3
4 r"r 0 0 + + + 0 0 + 0 + + 0 + 0 + 0 + + + 0 0 2+ 4
5 R2R2 0 + + + 0 0 + 0 0 + + + 0 + 0 + 0 + 0 + 0 2+ 5
6 R2R2 0 + + + 0 0 + + 0 + + + 0 + 0 + 0 + 0 + 0 2+ 6
7 R1R1 + + 0 0 + 0 0 + 0 0 + + + + 0 + 0 +S 0 + + 0 7
8 R1R1 + + 0 0 + 0 0 + 0 0 + + 0 + 0 0 + + + 0 0 0 8
9 RZR1 + + + - + 0 + + 0 + 0 0 + + 0 0 + + + 0 0 2+ 9
10 r?r + 0 0 + + 0 0 + 0 + 0 + + + 0 + 0 +S 0 + 0 0 10
      PEG
IAT*		  
Cord cell #1 E-   0  
Cord cell #2 E-   0  
Cord cell #3 E-   0  
Cord cell #4 E-   0  

* PEG = polyethylene glycol    IAT = indirect antiglobulin test

SELF TEST

1. Has anti-E been confirmed with an acceptable probability?

Answer

2. Based on these result (negative with enzymes and cord red cells), anti-Ch or anti-Rg were suspected. What is unique about the Chido/Rodgers system?

Answer