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Home Case Studies A-Level Case A4: Positive DAT in a Recently Transfused Nonagenarian Case Study A4 - Patient Phenotyping - Answer (Question 1)
Friday, 22 June 2018

Case Study A4 - Patient Phenotyping - Answer (Question 1)

Why were K and Jka phenotyping done using monoclonal anti-K and CDP-treated red cells, respectively?

K typing was done using monoclonal (IgM) anti-K because the patient has a positive DAT and typing by antiglobulin test is contraindicated unless the cells are first rendered DAT-negative.

Because monoclonal IgM anti-Jka is not available, typing could be done only by using CDP-treated cells that were DAT-negative.

Last modified on Thursday, 23 December 2010 14:38