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Case Study B7 - Antibody Investigation Results (Immediately Post-Transfusion)
 

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Home Case Studies B-Level Mini Case B7: Case of a Disappearing Antibody Case Study B7 - Antibody Investigation Results (Immediately Post-Transfusion)
Monday, 11 December 2017

Case Study B7 - Antibody Investigation Results (Immediately Post-Transfusion)

Cell Rh Rhesus Kell Duffy Kidd MNSs P Lewis Lu Results1 Results2
C D E c e Cw K k Kpa Fya Fyb Jka Jkb M N S s P1 Lea Leb Lua Gel
IAT
Gel
IAT
1 rr 0 0 0 + + 0 0 + 0 + 0 + 0 0 + + + +S + 0 0 0 w+
2 rr 0 0 0 + + 0 0 + 0 0 + + 0 0 + + + +S + 0 0 0 0
3 rr 0 0 0 + + 0 0 + 0 + 0 0 + 0 + + 0 + 0 + 0 0 0
4 r"r 0 0 + + + 0 0 + 0 + + 0 + 0 + 0 + + + 0 0 0 0
5 R2R2 0 + + + 0 0 + 0 0 + 0 + 0 + 0 + 0 + 0 + 0 0 0
6 R2R2 0 + + + 0 0 + + 0 + + + 0 + 0 + 0 + 0 + 0 0 0
7 R1R1 + + 0 0 + 0 0 + 0 0 + + + + 0 + 0 +S 0 + + 0 0
8 R1R1 + + 0 0 + 0 0 + 0 0 + + 0 + 0 0 + + + 0 0 0 0
9 RZR1 + + + - + 0 + + 0 + 0 0 + + 0 0 + + + 0 0 0 w+
10 r’r + 0 0 + + 0 0 + 0 + 0 + + + 0 + 0 +S 0 + 0 0 0
11 Auto 2+MFA 2+MFA

Results1: Patient's post-transfusion plasma     Results2: Patient's post-transfusion red cell eluate

NOTE: These tests were done using blood specimens drawn after the patient had been transfused with 2 units of O Rh negative RBC. The patient's plasma was also retested with the 6 RBC that tested positive before but they were now all negative by gel IAT.

Quiz

  1. What can account for the patient's post-transfusion plasma giving negative panel results?

    Answer

  2. Is an antibody identifiable using the patient's red cell eluate?

    Answer

  3. If the physician had decided to continue transfusing the patient at this stage, what would you advise regarding the compatibility of such transfusions, all of which appear to be compatible in the crossmatch?

    Answer

Last modified on Sunday, 06 November 2016 11:41